Expert insights on IVD antibodies, immunoassay development, and diagnostic reagents from Sekbio's technical team
A practical Q&A covering checkerboard ELISA screening, KD affinity targets, colloidal gold vs. fluorescent microsphere conjugation requirements, recombinant vs. hybridoma antibody sourcing, and hook effect troubleshooting — for IVD R&D engineers building POCT strips.
A deep dive into the structural biology and antiviral mechanism of MxA — why its interferon-exclusive induction logic makes it the most diagnostically specific blood biomarker for viral infection, and what IVD developers need to know about building CLIA and LFA assays around it.
China's MOST has opened the 2026 Batch 2 Intergovernmental S&T Cooperation program — funding joint R&D between Chinese and international partners. Learn which directions suit IVD and antibody companies, how to find a partner, and how to apply before the June 25 deadline.
The Shenzhen Chapter of SYSU Alumni Association toured Sekbio's ISO 13485-certified R&D labs, cleanrooms, and production QC. A constructive dialogue on IVD industry challenges, academic partnerships, and investment opportunities.
A comprehensive review of Ebola virus nucleoprotein — its molecular structure, three forms in patient blood (virion, extracellular vesicles, free from lysis), and why NP outperforms VP40 and GP as a rapid diagnostic test target.
Matching capture and detection antibodies for sandwich immunoassays: key criteria including epitope mapping, affinity thresholds, and practical optimization tips for IVD developers.
From antigen coating optimization to assay validation — a step-by-step guide for diagnostic assay developers building ELISAs for routine IVD workflows.
Why CHO cells dominate recombinant protein production for diagnostics. A technical deep-dive into glycosylation, scalability, and what it means for your IVD assay antigen performance.
Mammalian vs. insect vs. bacterial: which expression platform is right for your IVD assay? A technical comparison covering glycosylation, yield, cost, and regulatory considerations.
WHO confirmed an Andes hantavirus cluster aboard the MS Hondius in May 2026. This technical guide covers hantavirus biology, the IgM/IgG diagnostic window, and a step-by-step strategy for developing serological assays.
HRP2 gene deletions in P. falciparum are rendering standard malaria RDTs blind worldwide. Discover how GAPDH and DHFR-TS — essential, undeletable enzymes — are leading the race toward evolution-proof diagnostics.
Deep dive into antigenic variation: from Trypanosoma brucei's coat switching to HIV's predictable escape pathways. Explore the molecular disguise mechanisms pathogens use to evade the immune system and how modern diagnostics catch them.
Comprehensive guide to Vitamin D detection using ELISA for routine IVD workflows. Learn about assay optimization, performance parameters, and troubleshooting tips for accurate 25-hydroxyvitamin D measurement.
Explore the development of rapid test kits for Nipah virus detection, including assay design challenges, sensitivity requirements, and implementation strategies for outbreak control.
Detailed overview of Cholera O1 antibodies, their applications in diagnostic assay development, and best practices for ensuring specificity and sensitivity in cholera detection systems.
Learn how Sekbio helped a diagnostic manufacturer achieve sub-pg/mL sensitivity for cardiac troponin I detection through advanced antibody engineering and assay optimization techniques.
Introducing our new IL-6 antibody pair with enhanced sensitivity for detecting cytokine levels in sepsis and COVID-19 patients. Performance data and application examples included.
Comprehensive guide to selecting optimal antibody pairs for sandwich immunoassays, covering epitope mapping, affinity considerations, and validation protocols for reliable assay performance.