Human Progastrin-releasing Peptide (ProGRP)

ProGRP is a precursor of a neuropeptide hormone called a gastrin-releasing peptide (GRP) and is frequently produced by SCLC cells. Circulating proGRP levels serve as a reliable marker in patients with SCLC and is the most sensitive marker for discriminating SCLC from benign lung diseases. Progrp marker is rarely elevated in patients with other malignancies or mild conditions except in patients with renal insufficiency, neuroendocrine tumors of the lung, and medullary thyroid carcinoma. As for other tumor markers, we also provide a tumor markers list for your convenience.


ProGRP is a recently identified biomarker of small cell lung cancer (SCLC).


The ProGRP antibody pair's sensitivity is evaluated based on the Enzymatic Chemiluminescent immunoassay method.

Progastrin Releasing Peptide