Fibrinolytic enzyme dissolves cross-linked fibrin clots in the blood, and one of the specific degradation products is D-dimer. The increase of D-dimer level indicates the existence of hypercoagulability and secondary hyperfibrinolysis in vivo.
Therefore, we use D-dimer detection reagent in the clinical diagnosis of diffuse intravascular coagulation (DIC), deep vein thrombosis (DVT), pulmonary embolism, myocardial infarction, cerebral infarction, etc. We can use the D-dimer level for diagnosing thrombotic diseases and for the dosage monitoring and therapeutic effect observation of thrombolytic medicines.
SEKBIO is now offering Mouse anti-human D-Dimer mAb and Humanized anti-human D-Dimer mAb for D-Dimer detection usage.
|Mouse Anti-human D-Dimer mAb|
For immunodiagnostic: ELISA, LFA, CLIA
|Humanized Anti-human D-Dimer mAb|
There is fibrin in the blood, and fibrin is activated and hydrolyzed to produce specific degradation products called "fibrin degradation products. D-dimer is a simple degradation product of fibrin, and an increased level of D-dimer indicates that the body. There are hypercoagulable states and secondary hyperfibrinolysis. Therefore, the concentration of D-dimer is of great significance for the diagnosis, efficacy evaluation, and prognosis judgment of thrombotic diseases.
D-dimer is one of the degradation products of cross-linked fibrin and is a unique metabolite of secondary fibrinolysis. The anti-D-dimer monoclonal antibody is coated on latex particles. If D-dimer is present in recipient plasma, it will produce an antigen-antibody reaction, and latex particles will aggregate. D-dimer is positive, an observation index for diagnosing DIC and observing the effectiveness of thrombolytic therapy.
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