Cardiac Troponin T (cTnT)
An important marker for diagnosing myocardial injury
Cardiac Troponin T (cTnT) is a vital muscle calcium protein present in cardiac muscle cells. It plays a crucial role in regulating calcium ions during muscle contraction, serving as a key factor in muscle contraction control.
As a highly specific biomarker, cTnT is normally found at very low concentrations in the bloodstream. However, in cases of cardiac muscle cell damage, troponin T is released into the blood, leading to a significant increase in its levels. Consequently, measuring cTnT levels in the blood has emerged as a crucial diagnostic indicator for identifying myocardial injury, particularly in the diagnosis of myocardial infarction.
The elevated levels of cTnT can offer early insights into the extent and scope of myocardial injury, enabling healthcare professionals to make accurate diagnoses and develop effective treatment plans promptly.
Furthermore, cTnT serves as a valuable tool for assessing the risk of cardiovascular disease. Research has demonstrated a correlation between cTnT levels and cardiovascular disease risk, particularly in patients already affected by cardiovascular conditions. Monitoring changes in cTnT levels can provide valuable information on the progression and prognosis of cardiovascular disease.
Cardiac Troponin T (cTnT) Antibody Marker Products
Product Name | Cat. No. | Application Platform | Recommended Methods |
cTnT Antibody | S03-CTNT-21 | CLIA/ELISA/ LFA Capture | Double sandwich method |
cTnT Antibody | S03-CTNT-23 | CLIA/ELISA/ LFA Detection | Double sandwich method |
The advantages of Cardiac Troponin T (cTnT) Antibody Marker:
Cost-effective
Highly specific
Highly sensitive
We are committed to providing high-quality biological reagents to promote advances in medical research and diagnostic technologies. If you have any questions or needs, please feel free to contact us.
Sekbio cTnT Antibodies/Antigens
1.cTnT Antibodies/Antigens Information
Antibody# S03-CTNT-21 (Capturing) | |
Description: Class: From: Molecular: Form: Purity: Buffer: Isotype: Application: Epitope Storage | CTNT antibody Monoclonal Antibody Mouse 150 KD Solution (SDS-PAGE) >90% 10mM PBS , 0 .02% NaN3 IgG1 Capture aa131- 145 Store at -20±5℃ |
Antibody# S03-CTNT-23 (Detection) | |
Description: Clone : Class : From: Molecular: Form: Purity Buffer: Isotype Application: Epitope Storage | CTNT antibody E16H8 Monoclonal Antibody Mouse 150 KD Solution (SDS-PAGE) >90% 10mM PBS, 0 .02% NaN3 IgG1 Detection aa120- 130 Store at 2-8℃ |
| Antigen# S03-CTNT-Ag | |
Description: Class : From: Molecular: Form: Purity Buffer: Storage | Recombinant cTnT antigen CTnT Recombinant Antigen E .coli 70 KD Solution (SDS-PAGE) >80% 250mM Glycine +25mM Tris- HCl + 1/K SDS Store at -20±5℃ |
2. Recommended Platform and pairing
Antibody pairing has been verified to be used on ELISA, CLIA, Lateral Flow, and Latex turbidity platforms. Applying to other platforms is possible. It is recommended to verify and adjust according to the actual situation.
Capturing: S03-CTNT-21, Detection: S03-CTNT-23
3. Species Reactivity
Available for humans, other species not tested.
4. Storage
S03-CTNT-21 and CTNTAG1 should be stored at 2-8°C for the short term (less than two weeks) and at -20±5°C for a long time. Avoid freeze/thaw.
S03-CTNT-23 Please store at 2-8 ℃
5. Internal Performance evaluation
On the CLIA platform, using Sekbio recommended antibody pair with Roche's reagents, the correlation R2 was 0.9083 (n=73).
Figure 1: Comparative test results of Sekbio's cTnT antibody pair on the CLIA platform and Roche ECLIA reagents for clinical samples.
6. cTnT Antibodies/Antigens benefits
Detection range 0 .01~25 ng/ml。
Sensitivity requirements are easy to achieve.
High correlation with Roche's reagents.
Having a certain correlation with cTnI.
