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Cardiac Troponin T (cTnT)

An important marker for diagnosing myocardial injury


Cardiac Troponin T (cTnT) is a vital muscle calcium protein present in cardiac muscle cells. It plays a crucial role in regulating calcium ions during muscle contraction, serving as a key factor in muscle contraction control.

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As a highly specific biomarker, cTnT is normally found at very low concentrations in the bloodstream. However, in cases of cardiac muscle cell damage, troponin T is released into the blood, leading to a significant increase in its levels. Consequently, measuring cTnT levels in the blood has emerged as a crucial diagnostic indicator for identifying myocardial injury, particularly in the diagnosis of myocardial infarction.

The elevated levels of cTnT can offer early insights into the extent and scope of myocardial injury, enabling healthcare professionals to make accurate diagnoses and develop effective treatment plans promptly.

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Furthermore, cTnT serves as a valuable tool for assessing the risk of cardiovascular disease. Research has demonstrated a correlation between cTnT levels and cardiovascular disease risk, particularly in patients already affected by cardiovascular conditions. Monitoring changes in cTnT levels can provide valuable information on the progression and prognosis of cardiovascular disease.

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Cardiac Troponin T (cTnT) Antibody Marker Products

Product Name

Cat. No.

Application Platform

Recommended Methods

cTnT Antibody

S03-CTNT-21

CLIA/ELISA/ LFA

Capture

Double sandwich method

cTnT Antibody

S03-CTNT-23

CLIA/ELISA/ LFA

Detection

Double sandwich method


The advantages of Cardiac Troponin T (cTnT) Antibody Marker:

  • Cost-effective

  • Highly specific

  • Highly sensitive


We are committed to providing high-quality biological reagents to promote advances in medical research and diagnostic technologies. If you have any questions or needs, please feel free to contact us.


Sekbio cTnT Antibodies/Antigens


1.cTnT Antibodies/Antigens Information

Antibody# S03-CTNT-21 (Capturing)

Description:

Class:

From:

Molecular:

Form:

Purity:

Buffer:

Isotype:

Application:

Epitope

Storage

CTNT antibody

Monoclonal Antibody

Mouse

150 KD

Solution

(SDS-PAGE) >90%

10mM PBS , 0 .02% NaN3

IgG1

Capture

aa131- 145

Store at -20±5℃

Antibody# S03-CTNT-23 (Detection)

Description:

Clone :

Class :

From:

Molecular:

Form:

Purity

Buffer:

Isotype

Application:

Epitope

Storage

CTNT antibody

E16H8

Monoclonal Antibody

Mouse

150 KD

Solution

(SDS-PAGE) >90%

10mM PBS, 0 .02% NaN3

IgG1

Detection

aa120- 130

Store at 2-8℃

Antigen# S03-CTNT-Ag

Description:

Class :

From:

Molecular:

Form:

Purity

Buffer:

Storage

Recombinant cTnT antigen

CTnT Recombinant Antigen

E .coli

70 KD

Solution

(SDS-PAGE) >80%

250mM Glycine +25mM Tris- HCl + 1/K SDS

Store at -20±5℃


2. Recommended Platform and pairing

Antibody pairing has been verified to be used on ELISA, CLIA, Lateral Flow, and Latex turbidity platforms. Applying to other platforms is possible. It is recommended to verify and adjust according to the actual situation.

Capturing: S03-CTNT-21, Detection: S03-CTNT-23


3. Species Reactivity

Available for humans, other species not tested.


4. Storage

S03-CTNT-21 and CTNTAG1 should be stored at 2-8°C for the short term (less than two weeks) and at -20±5°C for a long time. Avoid freeze/thaw.

S03-CTNT-23 Please store at 2-8 ℃


5. Internal Performance evaluation

On the CLIA platform, using Sekbio recommended antibody pair with Roche's reagents, the correlation R2 was 0.9083 (n=73).

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Figure 1: Comparative test results of Sekbio's cTnT antibody pair on the CLIA platform and Roche ECLIA reagents for clinical samples.



6. cTnT Antibodies/Antigens benefits

Detection range 0 .01~25 ng/ml。

Sensitivity requirements are easy to achieve.

High correlation with Roche's reagents.

Having a certain correlation with cTnI.




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