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Cardiac Markers

Our cardiac marker antigens/antibodies are suitable for the diagnostics and risk stratification of patients with chest pain and suspected ACS and for management and prognosis in patients with acute heart failure, pulmonary embolism, and other disease states.

Sekbio provides high-quality cardiac markers. The cardiac markers tests include Cardiac troponin I (cTnI), Myoglobin (Myo), Creatine kinase-MB (CKMB), Heart-type Fatty Acid Binding Protein (H-FABP), D-Dimer, N-terminal pro B type Natriuretic Peptide (NT-proBNP), Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9).

We have done comparison experiments with mainstream diagnostic kits or mainstream antibodies/antigens as the benchmark to verify the performance of our products.

Our cardiac markers are suitable for a full range of diagnostic platforms, which include: Tubular chemiluminescence immunoassay, Micro-plate chemiluminescence immunoassay, ELISA. Colloidal gold POCT, Quantitative/qualitative fluorescent lateral flow method, etc.

Cardiac Markers Products

Cardiac Troponin I (cTnI)


Antibody

Application

Mouse anti-human cTnI mAb

For immunodiagnostic: ELISA, LFA, CLIA


Humanized anti-human cTnI mAb
Recombinant anti-human human cTnI mAb


AntigenApplication
Recombinant human cardiac troponin IC complex I (cTnI-C-I)

For immunodiagnostic: ELISA, LFA, CLIA


Recombinant human cardiac troponin IC complex II (cTnI-C-II)


Myoglobin (Myo)


Antibody

Application

Mouse Myo mAb

For immunodiagnostic: ELISA, LFA, CLIA



Antigen

Application

Recombinant Myo Antigen

For immunodiagnostic: ELISA, LFA, CLIA



Creatine Kinase-MB (CKMB)

Antibody

Application

Mouse Anti-human CKMB mAb

For immunodiagnostic: ELISA, LFA, CLIA


Humanized Anti-human CKMB mAb


Heart-type Fatty Acid Binding Protein (H-FABP)


AntibodyApplication
Mouse Anti-human FABP mAb

For immunodiagnostic: ELISA, LFA, CLIA

Recombinant Antigen (H-FABP)
Humanized Anti-human FABP mAb


AntigenApplication
Recombinant Antigen (H-FABP)

For immunodiagnostic: ELISA, LFA, CLIA


D-Dimer

NameApplication
Mouse Anti-human D-Dimer mAb

For immunodiagnostic: ELISA, LFA, CLIA

Humanized Anti-human D-Dimer mAb


N-terminal Pro B Type Natriuretic Peptide (NT-proBNP)


AntibodyApplication
Sheep anti-human NT-proBNP mAb

For immunodiagnostic: ELISA, LFA, CLIA

Mouse anti-human NT-proBNP mAb
Humanized anti-human NT-proBNP mAb


Antigen

Application

Recombinant human NT-proBNP antigen

For immunodiagnostic: ELISA, LFA, CLIA


Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)


AntibodyApplication
Anti-human PCSK9 Monoclonal Antibody

For immunodiagnostic: ELISA, LFA, CLIA


AntigenApplication
Recombinant PCSK9 Protein

For immunodiagnostic: ELISA, LFA, CLIA


What are Cardiac Markers?

Cardiac markers mainly include troponin T (troponin T), troponin I (troponin I), creatine kinase isoenzyme mass (CK-MBmass), and myoglobin (myoglobin). Troponin comprises three subunits, each of which has an independent structure and different regulatory roles. Cardiac troponin mediates the interaction between actin and myosin under the participation of calcium ions, thereby maintaining the relaxation and contraction of cardiac muscle. When the myocardial cell membrane is intact, cardiac troponin will not penetrate the cell membrane and enter the blood circulation. When the myocardial cell membrane is damaged, troponin can be released into the blood. The troponin concentration in the blood circulation is proportional to the procedure of myocardial damage. It has a half-life of up to 15 days, the best indicator for retrospective detection.

Cardiac Markers Test

Detecting cardiac markers is the key to diagnosing and treating cardiovascular diseases. The development of laboratory medicine for cardiac markers directly promotes the diagnosis and treatment of clinical cardiovascular diseases. It is a combination of various test indicators that reflect the different stages of heart disease and can be sensitively found in the early stage of heart disease. Cardiac markers test is inexpensive, can be continuously monitored dynamically, and is almost non-invasive.

Products