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Tumor Marker

A tumour marker is a chemical substance that reflects the presence of a Tumor. It is present in malignant tumour cells, not in normal adult tissues, and substances abnormally produced by malignant tumour cells or by the host's response to tumour stimulation created it.

Their presence or quantitative changes can indicate the nature of the tumour to understand the histogenesis, cell differentiation, and cell function of the tumour.

Detection of tumour markers has the following functions:

  • Early detection of tumour;

  • Tumour census and screening;

  • Diagnosis, differential diagnosis and staging of tumours;

  • Monitoring the efficacy of surgery, chemotherapy and radiotherapy for tumour patients;

  • Indicators of tumour recurrence;

  • Prognosis of tumour;

  • Looking for the primary foci of metastases of unknown origin.

Tumor Marker Products

CA50

Antibody

Application

Mouse anti-human CA50 mAb

For immunodiagnostic: ELISA, LFA, CLIA

Humanized anti-human CA50 mAb


CA125

AntibodyApplication
Mouse anti-human CA125 mAb

For immunodiagnostic: ELISA, LFA, CLIA

Humanized anti-human CA125 mAb



CA242

Antibody PairApplication
Mouse anti-human CA242 mAb

For immunodiagnostic: ELISA, LFA, CLIA

Humanized anti-human CA242 mAb


CA15-3

AntibodyApplication
Mouse anti-human CA15-3 mAb

For immunodiagnostic: ELISA, LFA, CLIA

Humanized anti-human CA15-3 mAb


CA19-9

AntibodyApplication
Mouse anti-human CA19-9 mAb

For immunodiagnostic: ELISA, LFA, CLIA

Humanized anti-human CA19-9 mAb


CA72-4

AntibodyApplication
Mouse anti-human CA72-4 mAb

For immunodiagnostic: ELISA, LFA, CLIA

Humanized anti-human CA72-4 mAb


Pepsinogens I (PGI)


AntibodyApplication
Anti-human PGI monoclonal antibody

For immunodiagnostic: ELISA, LFA, CLIA



AntigenApplication
PGI antigen

For immunodiagnostic: ELISA, LFA, CLIA


Human Epididymis 4 (HE4)


NameApplication
Recombinant human HE4 protein (Prokaryotic HE4 full-length protein)

For immunodiagnostic: ELISA, LFA, CLIA


Prostate-Specific Antigen (PSA)


AntibodyApplication
Mouse anti-human PSA mAb

For immunodiagnostic: ELISA, LFA, CLIA

Humanized anti-human PSA mAb
Mouse anti-human free PSA mAb



AntigenApplication
Prostate-Specific Antigen (Eukaryotic expression)

For immunodiagnostic: ELISA, LFA, CLIA


Squamous Cell Carcinoma (SCC)


AntibodyApplication
Mouse anti-human SCC mAb

For immunodiagnostic: ELISA, LFA, CLIA

Humanized anti-human SCC mAb
Prokaryotic expression antigen (full length)



AntigenApplication
Prokaryotic expression antigen (full length)For immunodiagnostic: ELISA, LFA, CLIA


Neuron-Specific Enolase (NSE)


AntibodyApplication
Mouse anti-human NSE mAb

For immunodiagnostic: ELISA, LFA, CLIA



AntigenApplication
Recombinant human neuron-specific enolase (Prokaryotic NSE protein full length)

For immunodiagnostic: ELISA, LFA, CLIA


CEA

Tumor Antigens

Tumor antigens generally refer to new or overexpressed antigenic substances during the occurrence and development of tumors.


The possible mechanisms for the body to produce tumor antigens are: 1) gene mutation; 2) the activation of genes that were not expressed initially during the process of cell carcinogenesis; 3) abnormalities in some aspects of the antigen synthesis process (such as abnormal glycosylation leading to the production of unique protein degradation products) ); abnormal and ectopic expression of antigens or differentiation antigens during embryonic stage; ⑤ overexpression of specific gene products, significantly signal transduction molecules; ⑥ expression of exogenous genes (such as viral genes).

Cancer Antigen

According to the specificity of cancer antigens, cancer antigens are divided into (1) Tumor-specific antigens (2) Tumor-associated antigens.


Tumor-specific antigen (TSA) is a neoantigen-specific to tumor cells or exists only in specific but not in normal cells.


Tumor-associated antigen (TAA) refers to antigens peculiar to non-tumor cells and exist in normal cells and other tissues. Still, their content is significantly increased when cells become cancerous.

Products