Testosterone (Testo)

Testosterone is the primary male sex hormone and an anabolic steroid. In male humans, testosterone plays a vital role in developing male reproductive tissues such as the testes and prostate and promoting secondary sexual characteristics such as increased muscle and bone mass and the growth of body hair.

The increased Testo level may be caused by: tumor, hermaphroditism, polycystic ovary syndrome, etc.

The decreased level reflects testis hypoplasia, hypophysis of the anterior lobe, cancer, etc. Combined with serum LH and FSH test results, it can identify primary or secondary testicular dysfunction and precocious puberty in adolescent children.

The performance data of the Testosterone (TES) Rapid Quantitative Test Kit (FIA)

Manufacturer	SEKBIO
Parameter	Testosterone (TES) Rapid Quantitative Test Kit (FIA)
Linearity	0.2~15ng/ml
Detection limit	0.2ng/mL
Benchmark product	Roche

1 Limit of detection

Result(C/T)	Concentration
Result(C/T)	0	0.18
1	0.64100	0.96675
2	0.79513	0.91924
3	0.73527	1.06822
4	0.77956	0.86043
5	0.75007	1.10303
6	0.63345	0.94187
7	0.78466	0.84868
8	0.69630	0.95063
9	0.71701	1.08039
10	0.70040	1.02653
11	0.76801	1.11575
12	0.64208	0.89674
13	0.79987	1.05212
14	0.68063	0.91094
15	0.72378	0.82531
16	0.67849	0.96335
17	0.66497	0.90646
18	0.75392	1.03400
19	0.78819	0.91084
20	0.65704	0.88530
AVE	0.71949	0.96333
SD	0.05621	/
AVE+2*SD	0.83191	/
regression equation	y=1.35465x+0.71949
LoB(ng/mL)	0.08299

2 Linear

Cal	Concentration	Result	AVERAGE
S1	0.18	0.19	0.18
		0.17
		0.17
S2	0.52	0.48	0.53
		0.57
		0.54
S3	1.36	1.44	1.35
		1.34
		1.27
S4	4.46	4.17	4.47
		4.98
		4.25
S5	10.03	9.98	10.25
		10.53
		10.25
S6	16.04	15.45	15.36
		15.30
		15.34

3 Accuracy

Cal	concentration	Result	Bias
A1	0.52	0.51	-1.3%
		0.48	-8.7%
		0.47	-9.8%
A2	1.36	1.47	7.8%
		1.31	-3.5%
		1.37	0.9%
A3	10.03	9.68	-3.5%
		10.84	8.1%
		10.18	1.5%

4 Precision

Cal	Concentration	Cal	Concentration	Cal	Concentration
R1	0.52	R2	1.56	R3	8.62
	0.51		1.52		8.94
	0.46		1.27		9.19
	0.45		1.55		9.11
	0.50		1.21		9.81
	0.59		1.23		9.00
	0.53		1.50		11.24
	0.59		1.41		10.81
	0.53		1.21		9.43
	0.56		1.38		10.45
AVE	0.52	AVE	1.38	AVE	9.66
SD	0.05	SD	0.14	SD	0.89
CV	8.9%	CV	10.4%	CV	9.2%

5 Method Comparison

Sample	Roche	Sekbio	Sample	Roche	Sekbio
1	6.17	5.14	31	4.20	4.08
2	10.37	11.04	32	3.45	3.55
3	4.30	4.16	33	0.77	0.95
4	11.19	11.38	34	13.24	12.21
5	0.83	0.79	35	6.56	6.66
6	0.81	0.78	36	0.31	0.30
7	0.42	0.43	37	1.88	2.00
8	1.19	1.17	38	0.79	0.96
9	2.51	2.30	39	1.20	1.07
10	2.93	2.62	40	0.90	0.78
11	0.92	0.91	41	2.14	2.24
12	1.38	1.27	42	9.33	8.11
13	2.88	3.02	43	0.44	0.45
14	0.31	0.28	44	9.91	10.73
15	10.06	8.67	45	10.18	8.86
16	10.50	8.48	46	0.95	0.90
17	11.04	9.99	47	0.98	1.06
18	5.41	6.14	48	6.35	6.80
19	3.01	3.08	49	1.42	1.64
20	0.22	0.25	50	0.51	0.55
21	3.18	3.96	51	0.53	0.56
22	8.94	7.79	52	8.45	9.89
23	2.45	2.88	53	1.31	1.19
24	1.32	1.26	54	1.45	1.32
25	0.20	0.20	55	10.58	11.31
26	4.71	4.87	56	2.47	2.42
27	2.24	2.25	57	0.35	0.32
28	8.56	7.70	58	1.01	1.10
29	0.20	0.23	59	0.25	0.21
30	2.41	2.24	60	7.56	7.66

Testosterone (Testo) Products

Antibody	Application
Sheep Anti-human Testo mAb	For immunodiagnostic: ELISA, LFA, CLIA

Testosterone (Testo) Product Diagnostic Performance

Testosterone Intro

Testosterone, with the molecular formula C19H28O2, is a steroid hormone secreted by the testes of men or the ovaries of women. It has the functions of maintaining muscle strength and mass, maintaining bone density and strength, refreshing, and improving physical fitness. The adrenal glands also secrete a small amount of testosterone.

Testosterone is a secreted glycoprotein initially identified from the enrichment medium of mouse Sertoli cells. A small molecular weight cytoskeleton-associated protein binds tightly to the cell surface through receptor-associated proteins.

Products

SEKBIO Updates

World Hemophilia Day ： Raise Awareness of Bleeding Disorders Read More >