High-Purity Nucleocapsid Protein (N-Protein) for Sensitive HFRS Diagnostic Assays
Hantaan virus (HTNV) is a major cause of Hemorrhagic Fever with Renal Syndrome (HFRS). In clinical diagnostics, the Nucleocapsid (N) protein is the most widely used antigen because it is expressed at high levels and induces a robust antibody response within the first week of symptoms.
Sekbio's HTNV-181 is a recombinant N-protein engineered for maximum diagnostic performance. It has been strictly validated in Indirect ELISA and Lateral Flow Immunoassays (LFA), making it an ideal raw material for high-sensitivity diagnostic kits used in clinical laboratories and point-of-care settings.
Hantavirus symptoms often overlap with influenza or other febrile illnesses. Accurate serological testing (IgM/IgG) is critical for triage, especially in endemic regions like Asia and Europe. Our antigen provides the reliability needed for early detection and epidemic surveillance.
The following data represents internal quality control results using Sekbio HTNV-181 in an Indirect ELISA format against confirmed patient serum panels.
| Panel Group | Sample Type | Average OD450 | Signal/Noise (S/N) |
|---|---|---|---|
| HTNV Positive (Group A) | IgM Positive | 2.684 | 20.6 |
| HTNV Positive (Group B) | IgG Positive | 3.120 | 24.0 |
| Healthy Control | IgM/IgG Negative | 0.130 | 1.0 |
| Cross-Reactive Panel | RF/Non-specific | 0.195 | 1.5 |
*Coating concentration: 1.5 μg/mL. Results may vary based on specific assay conditions and blocking buffers.
Ideal for Indirect or IgM-capture ELISA formats. High purity ensures minimal background and excellent signal differentiation for clinical diagnostic labs.
Optimized for colloidal gold or fluorescent bead conjugation. Provides rapid results (15-20 min) suitable for field surveillance and emergency triage.
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