Kanamycin & Neomycin Monoclonal Antibodies for Veterinary Drug Residue ELISA & LFA IVD Development
An aminoglycoside residue antibody is a monoclonal antibody raised against an aminoglycoside antibiotic hapten — a small-molecule drug conjugated to a carrier protein such as BSA or OVA — used to build competitive ELISA and lateral flow (LFA) immunoassays for veterinary drug residue detection. Aminoglycosides are broad-spectrum antibiotics widely used in veterinary medicine to treat bacterial infections across livestock, poultry, and aquaculture. Unlike some drug classes that are banned outright, aminoglycosides are generally permitted for veterinary use but carry established Maximum Residue Limits (MRLs) in most jurisdictions, because human consumption of aminoglycoside residues carries risks of nephrotoxicity (kidney damage) and ototoxicity (hearing damage). This makes accurate, sensitive residue screening — rather than simple ban-compliance testing — the central purpose of aminoglycoside antibody-based assays.
Sekbio's kanamycin and neomycin antibodies documented on this page are new additions to the aminoglycoside portfolio, complementing the streptomycin antibody already available from Sekbio and documented in full on the Antibiotic Residue Antibody hub page. Kanamycin, neomycin, and streptomycin together represent three of the most commercially significant aminoglycoside antibiotics in veterinary use, and testing programs that screen for the full aminoglycoside class typically require antibodies against all three (plus attention to structurally related compounds such as paromomycin, amikacin, and dihydrostreptomycin, which can cross-react with these antibodies).
Sekbio's kanamycin monoclonal antibody and matching BSA conjugate achieve an IC50 of 0.5 ppb, ELISA sensitivity of 0.5 ppb, and colloidal-gold LFA sensitivity of 50 ppb — providing sensitive, quantifiable detection suitable for both laboratory ELISA workflows and field-deployable rapid test strips. Sekbio's neomycin monoclonal antibody and matching BSA/OVA conjugate match this performance profile (IC50 0.5 ppb, ELISA sensitivity 0.5 ppb, LFA sensitivity 50 ppb) and additionally cross-react with paromomycin and amikacin — two structurally related aminoglycosides — providing broader aminoglycoside class coverage from a single antibody.
For laboratories building a complete aminoglycoside screening panel, Sekbio's streptomycin monoclonal antibody rounds out the offering: IC50 1 ppb, ELISA sensitivity 0.5 ppb, LFA sensitivity 50 ppb, and cross-reactivity with dihydrostreptomycin — the compound with which streptomycin is often co-administered in veterinary combination products. Because streptomycin's full performance data, cross-reactivity profile, and pricing are already documented in detail elsewhere on the Sekbio site, readers who need the complete streptomycin technical data sheet should consult the Streptomycin Antibody Data on the Antibiotic Residue Antibody hub page rather than duplicating that content here.
Three aminoglycoside antibiotic targets for comprehensive residue screening in milk, meat, and aquaculture matrices.
| Target Antibiotic | Conjugate | IC50 | ELISA Sensitivity | LFA Sensitivity | Key Cross-reactivity | Price (1 mg) |
|---|---|---|---|---|---|---|
| Kanamycin (KAN) | BSA | 0.5 ppb | 0.5 ppb | 50 ppb | Class-specific | $895.52/mg |
| Neomycin (NEO) | BSA / OVA | 0.5 ppb | 0.5 ppb | 50 ppb | Paromomycin, Amikacin | $895.52/mg |
| Streptomycin (STR)* | See hub page | 1 ppb | 0.5 ppb | 50 ppb | Dihydrostreptomycin | $895.52/mg |
*Streptomycin summary data shown for aminoglycoside class completeness. Full streptomycin specifications, lot documentation, and extended cross-reactivity data are maintained on the Antibiotic Residue Antibody hub page. IC50 and sensitivity values from COA release testing in competitive ELISA format. Prices are reference list prices per 1 mg; OEM bulk-scale pricing for 10 mg to gram quantities is quoted on request. Contact info@sekbio.com for full performance data and matrix-specific extraction protocols.
Sub-ppb IC50 antibodies for kanamycin and neomycin, complementing Sekbio's established streptomycin antibody for complete aminoglycoside class coverage.
Sekbio's kanamycin monoclonal antibody achieves an IC50 of 0.5 ppb, matched with 0.5 ppb ELISA sensitivity — providing a sensitive, quantifiable detection capability for one of the most widely used veterinary aminoglycosides in livestock and dairy production.
Sekbio's neomycin monoclonal antibody (IC50 0.5 ppb) cross-reacts with paromomycin and amikacin, two structurally related aminoglycosides. This built-in cross-reactivity extends the practical screening coverage of a single antibody across three related compounds without requiring separate reagents for each.
Aminoglycosides are known to concentrate more heavily in kidney tissue than in muscle, making kidney a priority sample matrix in aminoglycoside residue monitoring. Sekbio's kanamycin and neomycin antibodies are designed to support extraction and testing protocols for both muscle and kidney tissue in meat residue screening programs.
Kanamycin and neomycin are commonly included in dairy antibiotic residue screening panels alongside β-lactams and streptomycin. Sekbio's antibodies support the multi-target ELISA and LFA panel formats that milk testing laboratories and processing plants rely on for routine farm-gate and in-line antibiotic screening.
Kanamycin, neomycin, and streptomycin all share a 50 ppb colloidal-gold LFA visual sensitivity in Sekbio's portfolio, simplifying the design of a combined aminoglycoside rapid test strip covering all three targets with consistent performance characteristics.
Rather than duplicating existing documentation, Sekbio's kanamycin and neomycin antibodies are designed as a direct complement to the streptomycin antibody already available and fully documented on the Antibiotic Residue Antibody hub page, giving kit developers a complete three-target aminoglycoside panel sourced from a single supplier.
Aminoglycosides are also used in fish and shrimp farming for bacterial disease control, making kanamycin and neomycin residue screening relevant to aquaculture export compliance programs alongside the dairy and meat testing applications more commonly associated with this antibiotic class.
MOQ is 1 mg per antibody for R&D evaluation, with OEM quantities from 10 mg to gram scale available for kit manufacturing. Sekbio's ISO 13485-certified Shenzhen facility supports quality-assured production with lot COA documentation. Explore the full Sekbio antibody catalog or contact our team for aminoglycoside panel development support.
Kanamycin and neomycin antibodies for dairy, meat, aquaculture, and honey aminoglycoside residue screening panels.
Raw milk antibiotic residue testing routinely includes aminoglycoside screening alongside β-lactam and tetracycline panels, since kanamycin, neomycin, and streptomycin are all used to treat mastitis and other bacterial infections in dairy cattle. Sekbio's kanamycin and neomycin antibodies support both farm-gate rapid test screening and processing-plant ELISA confirmation testing as part of comprehensive dairy antibiotic residue monitoring programs.
Because aminoglycosides concentrate more heavily in kidney tissue than in muscle, meat residue testing programs for beef, pork, and poultry frequently include kidney samples specifically to capture aminoglycoside residues that may not yet be detectable in muscle. Sekbio's kanamycin and neomycin antibodies support extraction and testing protocols across both tissue types.
Aminoglycosides, including kanamycin and neomycin, are used in fish and shrimp farming to manage bacterial disease outbreaks. Aquaculture exporters and processors use Sekbio's aminoglycoside antibodies to screen for residue compliance alongside other veterinary drug and dye residue targets relevant to seafood export markets.
Aminoglycoside antibiotics, including streptomycin, have documented use in some beekeeping operations for bacterial disease management. Honey testing laboratories rely on the aminoglycoside antibody panel — kanamycin, neomycin, and streptomycin — to support compliance testing and export documentation for honey producers and packers.
Technical and commercial questions from food safety IVD developers building aminoglycoside residue screening assays.
Aminoglycosides are a class of broad-spectrum antibiotics — including kanamycin, neomycin, and streptomycin — widely used in veterinary medicine to treat bacterial infections in livestock, poultry, and aquaculture. In humans, aminoglycoside residue consumption carries risks of nephrotoxicity (kidney damage) and ototoxicity (hearing damage), which is why most jurisdictions have established Maximum Residue Limits (MRLs) for aminoglycosides in animal-derived food rather than banning the class outright. Because aminoglycosides also tend to concentrate in kidney tissue relative to muscle, kidney samples often receive particular attention in residue monitoring programs.
Sekbio's kanamycin monoclonal antibody achieves an IC50 of 0.5 ppb in competitive ELISA format, with ELISA detection sensitivity of 0.5 ppb and colloidal-gold LFA rapid test strip sensitivity of 50 ppb. Kanamycin and its matching BSA conjugate are available for ELISA plate coating and LFA nitrocellulose membrane striping.
Yes. Sekbio's neomycin monoclonal antibody (IC50 0.5 ppb) is cross-reactive with paromomycin and amikacin, two structurally related aminoglycoside antibiotics. This cross-reactivity allows a single neomycin-based assay to provide broader aminoglycoside class coverage, which is useful for general aminoglycoside screening panels where identifying the specific drug is secondary to detecting any aminoglycoside contamination above the screening threshold.
Yes. Streptomycin is part of the same aminoglycoside antibiotic class as kanamycin and neomycin, and Sekbio supplies a streptomycin monoclonal antibody with IC50 1 ppb, ELISA sensitivity 0.5 ppb, LFA sensitivity 50 ppb, and cross-reactivity with dihydrostreptomycin. Full streptomycin antibody specifications, including detailed cross-reactivity and pricing data, are documented on Sekbio's Antibiotic Residue Antibody hub page — see Streptomycin Antibody Data for complete details.
Milk and dairy products are a primary matrix for kanamycin and neomycin screening panels, alongside meat — particularly muscle and kidney tissue, since aminoglycosides concentrate more heavily in kidney than in muscle. Aquaculture products and honey are also relevant matrices given aminoglycoside use in fish and shrimp farming and, in some regions, in beekeeping disease management.
Kanamycin, neomycin, and streptomycin monoclonal antibodies are each priced at a reference rate of $895.52 per mg, covering either the antibody itself or its matching hapten-BSA/OVA conjugate (1 mg each). MOQ is 1 mg per reagent for R&D evaluation, with OEM bulk quantities from 10 mg to gram scale available for ELISA and LFA test kit manufacturing. Contact info@sekbio.com for a formal quotation.
Yes. Both the kanamycin antibody and BSA conjugate, and the neomycin antibody and BSA/OVA conjugate, are validated for competitive ELISA microplate format and colloidal-gold lateral flow (LFA) rapid test strip format, each achieving 50 ppb LFA visual sensitivity. Contact info@sekbio.com for antibody conjugation protocols and matrix-specific extraction guidance.
Aminoglycoside testing is frequently combined with other antibiotic classes in dairy, meat, and aquaculture panels.
Full streptomycin monoclonal antibody specifications — including dihydrostreptomycin cross-reactivity, lot documentation, and pricing — are maintained on the Antibiotic Residue Antibody hub page, which also covers chloramphenicol, tetracycline, fluoroquinolone, and β-lactam residue antibodies.
Nitrofuran metabolites are frequently co-tested with aminoglycosides in aquaculture and shrimp export compliance panels. Review the Nitrofuran Metabolite Antibody data sheet for AOZ, SEM, AMOZ, and AHD performance specifications.
Browse the complete Sekbio antibody product catalog or contact our team to discuss multi-target veterinary drug residue panel development.
Request kanamycin or neomycin antibody evaluation kits, hapten conjugates, or discuss OEM ELISA and LFA kit development support.