Creatine Kinase-MB (CK-MB) is an isoenzyme of creatine kinase that is primarily found in myocardial cells, making it an important cardiac marker.
Key Functions
1.Presence in Myocardial Cells:
CK-MB is predominantly found in heart muscle cells, and its levels in the blood rise when the heart muscle is damaged.
2.Indicator of Myocardial Infarction:
CK-MB is a highly specific marker for myocardial infarction (MI). After the onset of MI, CK-MB levels rise within six hours, peak at 24 hours, and return to normal within 3-4 days.
3.Diagnosis of Myocardial Infarction:
Serum CK-MB levels are more reliable than electrocardiogram results for diagnosing myocardial infarction. The rapid increase in CK-MB levels after MI provides valuable diagnostic information.
Clinical Applications
1.Disease Diagnosis:
Elevated CK-MB levels are used for diagnosing myocardial infarction, muscular atrophy, and other conditions that involve muscle damage.
2.Myocardial Infarction Monitoring:
CK-MB is used to monitor the progression of myocardial infarction and assess the timing of myocardial injury.
